1ksx

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Current revision (09:04, 16 August 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ksx]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovine_papillomavirus Bovine papillomavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KSX FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ksx]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovine_papillomavirus Bovine papillomavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KSX FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ksy|1ksy]], [[1f08|1f08]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ksx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ksx OCA], [https://pdbe.org/1ksx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ksx RCSB], [https://www.ebi.ac.uk/pdbsum/1ksx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ksx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ksx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ksx OCA], [https://pdbe.org/1ksx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ksx RCSB], [https://www.ebi.ac.uk/pdbsum/1ksx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ksx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/VE1_BPV1 VE1_BPV1]] ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.
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[https://www.uniprot.org/uniprot/VE1_BPV1 VE1_BPV1] ATP-dependent DNA helicase required for initiation of viral DNA replication. It forms a complex with the viral E2 protein. The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Bovine papillomavirus]]
[[Category: Bovine papillomavirus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Enemark, E J]]
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[[Category: Enemark EJ]]
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[[Category: Joshua-Tor, L]]
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[[Category: Joshua-Tor L]]
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[[Category: Stenlund, A]]
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[[Category: Stenlund A]]
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[[Category: Dna-binding domain]]
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[[Category: Helicase]]
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[[Category: Initiator protein]]
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[[Category: Papillomavirus]]
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[[Category: Replication]]
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[[Category: Replication-dna complex]]
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Current revision

Crystal Structures of Two Intermediates in the Assembly of the Papillomavirus Replication Initiation Complex

PDB ID 1ksx

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