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2iuj

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(New page: 200px<br /> <applet load="2iuj" size="450" color="white" frame="true" align="right" spinBox="true" caption="2iuj, resolution 2.4&Aring;" /> '''CRYSTAL STRUCTURE OF...)
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==About this Structure==
==About this Structure==
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2IUJ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Glycine_max Glycine max]] with FE as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IUJ OCA]].
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2IUJ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Glycine_max Glycine max]] with FE as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2IUJ OCA]].
==Reference==
==Reference==
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[[Category: soybean lipoxygenase-b]]
[[Category: soybean lipoxygenase-b]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Oct 29 17:59:08 2007''
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:29:36 2007''

Revision as of 09:24, 30 October 2007


2iuj, resolution 2.4Å

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CRYSTAL STRUCTURE OF SOYBEAN LIPOXYGENASE-B

Overview

The lipoxygenase family of lipid-peroxidizing, nonheme iron dioxygenases, form products that are precursors for diverse physiological processes in, both plants and animals. In soybean (Glycine max), five vegetative, isoforms, VLX-A, VLX-B, VLX-C, VLX-D, VLX-E, and four seed isoforms LOX-1, LOX-2, LOX-3a, LOX-3b have been identified. In this study, we determined, the crystal structures of the substrate-free forms of two major vegetative, isoforms, with distinct enzymatic characteristics, VLX-B and VLX-D. Their, structures are similar to the two seed isoforms, LOX-1 and LOX-3, having, two domains with similar secondary structural elements: a beta-barrel, N-terminal domain containing highly flexible loops and an alpha-helix-rich, C-terminal catalytic domain. Detailed comparison of the ... [(full description)]

About this Structure

2IUJ is a [Single protein] structure of sequence from [Glycine max] with FE as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Crystal structures of vegetative soybean lipoxygenase VLX-B and VLX-D, and comparisons with seed isoforms LOX-1 and LOX-3., Youn B, Sellhorn GE, Mirchel RJ, Gaffney BJ, Grimes HD, Kang C, Proteins. 2006 Dec 1;65(4):1008-20. PMID:17022084

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