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Sandbox GGC3

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<StructureSection loadfiles='4G36''4G37' size='340' side='right' caption='Luciferin-4-monooxygenase. The wild-type luciferase in the adenylate-forming conformation with DLSA (PDB 4G36) and the cross-linked luciferase in the second catalytic conformation with DLSA (PDB 4G37)' scene=''>
<StructureSection loadfiles='4G36''4G37' size='340' side='right' caption='Luciferin-4-monooxygenase. The wild-type luciferase in the adenylate-forming conformation with DLSA (PDB 4G36) and the cross-linked luciferase in the second catalytic conformation with DLSA (PDB 4G37)' scene=''>
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Firefly luciferase, an oxygenase found in the common eastern firefly, is responsible for the ability of the firefly to exhibit bioluminescence. The enzyme, luciferin-4-monooxygenase, not sure <scene name='75/752266/Adenylate-forming/2'>adenylate-forming</scene> and <scene name='75/752266/Second_catalytic_conformation/2'>second catalytic conformation</scene>
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Firefly luciferase, an oxygenase found in the common eastern firefly, is responsible for the ability of the firefly to exhibit bioluminescence. The enzyme, luciferin-4-monooxygenase, catalyzes a multi-step oxidative decarboxylation of the luciferyl-AMP intermediate (LH2-AMP) to produce bioluminescence. <scene name='75/752266/Adenylate-forming/2'>adenylate-forming</scene> and <scene name='75/752266/Second_catalytic_conformation/2'>second catalytic conformation</scene>
== Function ==
== Function ==
[[Image:Common_Eastern_Firefly.jpg|thumb|left|The Common Eastern Firefly in a hand emitting a yellow hue, showing bioluminescence]]
[[Image:Common_Eastern_Firefly.jpg|thumb|left|The Common Eastern Firefly in a hand emitting a yellow hue, showing bioluminescence]]

Revision as of 16:37, 26 April 2021

Firefly Luciferase

Luciferin-4-monooxygenase. The wild-type luciferase in the adenylate-forming conformation with DLSA (PDB 4G36) and the cross-linked luciferase in the second catalytic conformation with DLSA (PDB 4G37)

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References

[1]

  1. ↑ Sundlov, J. A., Fontaine, D. M., Southworth, T. L., Branchini, B. R., Gulick, A. M. (2012). Crystal Structure of Firefly Luciferase in a Second Catalytic Conformation Supports a Domain Alternation Mechanism. Biochemistry 51 (33), 6493-6495. https://doi.org/10.1021/bi300934s
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