7oa5

==RUVA COMPLEXED TO A HOLLIDAY JUNCTION.==

<StructureSection load='7oa5' size='340' side='right'caption='[[7oa5]], [[Resolution|resolution]] 2.38&Aring;' scene=''>

<table><tr><td colspan='2'>[[7oa5]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_leprae Mycobacterium leprae] and [https://en.wikipedia.org/wiki/Mycobacterium_leprae_TN Mycobacterium leprae TN]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1bvs 1bvs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7OA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7OA5 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.378&#8491;</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7oa5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7oa5 OCA], [https://pdbe.org/7oa5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7oa5 RCSB], [https://www.ebi.ac.uk/pdbsum/7oa5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7oa5 ProSAT]</span></td></tr>

== Function ==

[https://www.uniprot.org/uniprot/RUVA_MYCLE RUVA_MYCLE] The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity).

==See Also==

*[[Helicase 3D structures|Helicase 3D structures]]

*[[Resolvase 3D structures|Resolvase 3D structures]]

[[Category: Mycobacterium leprae]]

[[Category: Roe SM]]