6wqw
From Proteopedia
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==Thermobacillus composti GH10 xylanase== | ==Thermobacillus composti GH10 xylanase== | ||
| - | <StructureSection load='6wqw' size='340' side='right'caption='[[6wqw]]' scene=''> | + | <StructureSection load='6wqw' size='340' side='right'caption='[[6wqw]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WQW FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6wqw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobacillus_composti Thermobacillus composti]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WQW FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wqw OCA], [https://pdbe.org/6wqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wqw RCSB], [https://www.ebi.ac.uk/pdbsum/6wqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wqw ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.102Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wqw OCA], [https://pdbe.org/6wqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wqw RCSB], [https://www.ebi.ac.uk/pdbsum/6wqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wqw ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/L0EGW1_THECK L0EGW1_THECK] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Enzymatic transformation of xylans into renewable fuels and value-added products is mediated by xylanases. Here we describe the biochemical and X-ray structural characterization of Thermobacillus composti GH10 xylanase (TcXyn10A) at 2.1 A resolution aiming to unravel details of its recognition of glucurono- and arabinoxylan at a molecular level. TcXyn10A improves the efficiency of pretreated lignocellulosic biomass hydrolysis by a commercial enzyme cocktail causing a 15.35 % increase in xylose release and 4.38 % glucose release after 24 h of reaction. The enzyme releases predominantly xylobiose and xylotriose, as well as MeGlcA3 x 3 (from beechwood glucuronoxylan) and a range of decorated xylooligosaccharides (XOS) from rye arabinoxylan, with Ara2 x 2 being the major product. The enzyme liberates XOS with the yields of 29.09 % for beechwood glucuronoxylan and 16.98 % for rye arabinoxylan. Finally, TcXyn10A has a high thermal stability, halotolerance, and resistance to ethanol, biochemical properties that can be desirable for a number of industrial applications. | ||
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| + | Transformation of xylan into value-added biocommodities using Thermobacillus composti GH10 xylanase.,Sepulchro AGV, Pellegrini VOA, Briganti L, de Araujo EA, de Araujo SS, Polikarpov I Carbohydr Polym. 2020 Nov 1;247:116714. doi: 10.1016/j.carbpol.2020.116714. Epub , 2020 Jul 3. PMID:32829841<ref>PMID:32829841</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6wqw" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Thermobacillus composti]] | ||
[[Category: Briganti L]] | [[Category: Briganti L]] | ||
[[Category: Polikarpov I]] | [[Category: Polikarpov I]] | ||
Current revision
Thermobacillus composti GH10 xylanase
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