This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7mhb
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of ATP-dependent protease ATPase subunit HslU in complex with Adenosine 5'-diphosphate== | ==Crystal structure of ATP-dependent protease ATPase subunit HslU in complex with Adenosine 5'-diphosphate== | ||
| - | <StructureSection load='7mhb' size='340' side='right'caption='[[7mhb]]' scene=''> | + | <StructureSection load='7mhb' size='340' side='right'caption='[[7mhb]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MHB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7mhb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brucella_abortus_2308 Brucella abortus 2308]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MHB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MHB FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mhb OCA], [https://pdbe.org/7mhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mhb RCSB], [https://www.ebi.ac.uk/pdbsum/7mhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mhb ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mhb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mhb OCA], [https://pdbe.org/7mhb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mhb RCSB], [https://www.ebi.ac.uk/pdbsum/7mhb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mhb ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HSLU_BRUA2 HSLU_BRUA2] ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.[HAMAP-Rule:MF_00249] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[ATPase 3D structures|ATPase 3D structures]] | ||
| + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Brucella abortus 2308]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
Current revision
Crystal structure of ATP-dependent protease ATPase subunit HslU in complex with Adenosine 5'-diphosphate
| |||||||||||
