1kg4
From Proteopedia
(Difference between revisions)
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<StructureSection load='1kg4' size='340' side='right'caption='[[1kg4]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='1kg4' size='340' side='right'caption='[[1kg4]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1kg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1kg4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KG4 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | < | + | |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg4 OCA], [https://pdbe.org/1kg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kg4 RCSB], [https://www.ebi.ac.uk/pdbsum/1kg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg4 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg4 OCA], [https://pdbe.org/1kg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kg4 RCSB], [https://www.ebi.ac.uk/pdbsum/1kg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/MUTY_ECOLI MUTY_ECOLI] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Gerchman | + | [[Category: Gerchman SE]] |
| - | [[Category: Gilboa | + | [[Category: Gilboa R]] |
| - | [[Category: Grollman | + | [[Category: Grollman AP]] |
| - | [[Category: Kilshtein | + | [[Category: Kilshtein A]] |
| - | [[Category: Kycia | + | [[Category: Kycia JH]] |
| - | [[Category: Shoham | + | [[Category: Shoham G]] |
| - | [[Category: Zharkov | + | [[Category: Zharkov DO]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the K142A mutant of E. coli MutY (core fragment)
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