1l3w

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<StructureSection load='1l3w' size='340' side='right'caption='[[1l3w]], [[Resolution|resolution]] 3.08&Aring;' scene=''>
<StructureSection load='1l3w' size='340' side='right'caption='[[1l3w]], [[Resolution|resolution]] 3.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1l3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. The March 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Cadherin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_3 10.2210/rcsb_pdb/mom_2008_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L3W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1l3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. The March 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Cadherin'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_3 10.2210/rcsb_pdb/mom_2008_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L3W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.08&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ncg|1ncg]], [[1nch|1nch]], [[1nci|1nci]], [[1edh|1edh]], [[1ff5|1ff5]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3w OCA], [https://pdbe.org/1l3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l3w RCSB], [https://www.ebi.ac.uk/pdbsum/1l3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l3w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l3w OCA], [https://pdbe.org/1l3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l3w RCSB], [https://www.ebi.ac.uk/pdbsum/1l3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l3w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CADHF_XENLA CADHF_XENLA]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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[https://www.uniprot.org/uniprot/CADHF_XENLA CADHF_XENLA] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: African clawed frog]]
 
[[Category: Cadherin]]
[[Category: Cadherin]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Boggon, T J]]
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[[Category: Xenopus laevis]]
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[[Category: Chappuis-Flament, S]]
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[[Category: Boggon TJ]]
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[[Category: Gumbiner, B M]]
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[[Category: Chappuis-Flament S]]
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[[Category: Murray, J]]
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[[Category: Gumbiner BM]]
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[[Category: Shapiro, L]]
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[[Category: Murray J]]
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[[Category: Wong, E]]
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[[Category: Shapiro L]]
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[[Category: Calcium binding]]
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[[Category: Wong E]]
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[[Category: Cell adhesion]]
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[[Category: Ectodomain]]
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[[Category: Extracellular]]
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[[Category: Metal binding protein]]
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Revision as of 09:09, 16 August 2023

C-cadherin Ectodomain

PDB ID 1l3w

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