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1lu1

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Current revision (06:28, 9 August 2023) (edit) (undo)
 
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<StructureSection load='1lu1' size='340' side='right'caption='[[1lu1]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='1lu1' size='340' side='right'caption='[[1lu1]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1lu1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dolichos_biflorus Dolichos biflorus]. The December 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LU1 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1lu1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vigna_unguiculata_subsp._cylindrica Vigna unguiculata subsp. cylindrica]. The December 2012 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''ABO Blood Type Glycosyltransferases'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2012_12 10.2210/rcsb_pdb/mom_2012_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LU1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LU1 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2G:N-ACETYL-2-DEOXY-2-AMINO-GALACTOSE'>A2G</scene>, <scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NGA:N-ACETYL-D-GALACTOSAMINE'>NGA</scene>, <scene name='pdbligand=PRD_900083:Forssman+antigen+fragment'>PRD_900083</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lu1 OCA], [https://pdbe.org/1lu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lu1 RCSB], [https://www.ebi.ac.uk/pdbsum/1lu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lu1 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lu1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lu1 OCA], [https://pdbe.org/1lu1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lu1 RCSB], [https://www.ebi.ac.uk/pdbsum/1lu1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lu1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LEC1_VIGUC LEC1_VIGUC]] Metalloglycoprotein, containing Ca, Mg, Mn, and Zn and the carbohydrates galactose, glucosamine, mannose, and fucose. It agglutinates erythrocytes of blood group A1. Has a high preference for GalNAc over Gal.
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[https://www.uniprot.org/uniprot/LEC1_VIGUC LEC1_VIGUC] Metalloglycoprotein, containing Ca, Mg, Mn, and Zn and the carbohydrates galactose, glucosamine, mannose, and fucose. It agglutinates erythrocytes of blood group A1. Has a high preference for GalNAc over Gal.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: ABO Blood Type Glycosyltransferases]]
[[Category: ABO Blood Type Glycosyltransferases]]
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[[Category: Dolichos biflorus]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Bouckaert, J]]
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[[Category: Vigna unguiculata subsp. cylindrica]]
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[[Category: Etzler, M E]]
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[[Category: Bouckaert J]]
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[[Category: Fernandez, E]]
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[[Category: Etzler ME]]
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[[Category: Hamelryck, T W]]
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[[Category: Fernandez E]]
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[[Category: Imberty, A]]
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[[Category: Hamelryck TW]]
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[[Category: Loris, R]]
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[[Category: Imberty A]]
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[[Category: Strecker, G]]
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[[Category: Loris R]]
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[[Category: Wyns, L]]
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[[Category: Strecker G]]
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[[Category: Dolichos biflorus seed lectin]]
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[[Category: Wyns L]]
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[[Category: Forssman disaccharide]]
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[[Category: Lectin]]
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[[Category: Legume lectin]]
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Current revision

THE STRUCTURE OF THE DOLICHOS BIFLORUS SEED LECTIN IN COMPLEX WITH THE FORSSMAN DISACCHARIDE

PDB ID 1lu1

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