Neurotrophin-4 (NFT-4) is a neuronal growth factor that influences nerve cell proliferation through selective and non-covalent interactions with the nerve growth factor receptor.
Function
NFT-4 functions as a growth factor in many biological pathways and processes to induce neuronal proliferation.
Biological Processes
Positive regulation of neurotrophin TRK receptor signaling pathway:
NFT-4 functions as a ligand when binding to neurotrophin receptor tyrosine kinase NTRK2. Auto-phosphorylated NTRK2 dimers that are formed on tyrosine residues in receptor tail as a result of NFT-4 binding.
Neuron projection morphogenesis:
Generating projection structures of a neuron,.
Ganglion mother cell fate determination, epidermis development, innervation
Nerve invading tissue and coming out
Disease
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
