2ffl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='2ffl' size='340' side='right'caption='[[2ffl]], [[Resolution|resolution]] 3.33&Aring;' scene=''>
<StructureSection load='2ffl' size='340' side='right'caption='[[2ffl]], [[Resolution|resolution]] 3.33&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2ffl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Giain Giain]. The February 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Small Interfering RNA'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_2 10.2210/rcsb_pdb/mom_2008_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FFL FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2ffl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Giardia_intestinalis Giardia intestinalis]. The February 2008 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Small Interfering RNA'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2008_2 10.2210/rcsb_pdb/mom_2008_2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FFL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FFL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonuclease_III Ribonuclease III], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.3 3.1.26.3] </span></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ffl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffl OCA], [https://pdbe.org/2ffl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ffl RCSB], [https://www.ebi.ac.uk/pdbsum/2ffl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ffl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ffl OCA], [https://pdbe.org/2ffl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ffl RCSB], [https://www.ebi.ac.uk/pdbsum/2ffl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ffl ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/DCL_GIAIC DCL_GIAIC] Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs.<ref>PMID:16410517</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 18:
</div>
</div>
<div class="pdbe-citations 2ffl" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2ffl" style="background-color:#fffaf0;"></div>
- 
-
==See Also==
 
-
*[[Dicer|Dicer]]
 
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Giain]]
+
[[Category: Giardia intestinalis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
-
[[Category: Ribonuclease III]]
 
[[Category: Small Interfering RNA]]
[[Category: Small Interfering RNA]]
-
[[Category: Adams, P D]]
+
[[Category: Adams PD]]
-
[[Category: Doudna, J A]]
+
[[Category: Doudna JA]]
-
[[Category: MacRae, I J]]
+
[[Category: MacRae IJ]]
-
[[Category: Hydrolase]]
+
-
[[Category: Paz domain]]
+
-
[[Category: Rna interference]]
+
-
[[Category: Rnai]]
+
-
[[Category: Translation]]
+

Revision as of 07:13, 8 February 2023

Crystal Structure of Dicer from Giardia intestinalis

PDB ID 2ffl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ffl"
Personal tools