Leukocyte immunoglobulin-like receptor

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*LIR-1; ligand-binding domain D1D2 27-221; ligand-binding domain D3D4 222-417
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*LILR; ligand-binding domain D1D2 27-221; ligand-binding domain D3D4 222-417
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**[[1g0x]], [[1ufu]] – hLIR-1 ligand-binding domain D1D2– human <br />
+
*LILRA2 subfamily A member 2
-
**[[1ugn]], [[1vdg]] – hLIR-1 ligand-binding domain D1D2 (mutant) <br />
+
-
**[[4ll9]] – hLIR-1 ligand-binding domain D3D4 <br />
+
-
*LIR-1 complexes
+
**[[2otp]] – hLILRA2 ligand-binding domain D1D2 - human<br />
-
**[[1p7q]] – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + POL polyprotein peptide<br />
+
*LILRA3 subfamily A member 3
-
**[[5knm]] – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + peptide<br />
+
-
**[[4no0]] – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + lymphocyte-specific protein peptide<br />
+
-
**[[3d2u]] – hLIR-1 ligand-binding domain D1D2 + herpesvirus UL18 + β-2 microglobulin + actin peptide<br />
+
-
**[[6ewa]], [[6ewc]] – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + peptide<br />
+
-
**[[6ewo]] – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + desmuslin peptide<br />
+
-
**[[6aee]], [[6k60]] – hLIR-1 ligand-binding domain D1D2D3D4 + class I MHC + β-2 microglobulin + histone peptide<br />
+
-
*LIR-2
+
**[[3q2c]] – hLILRA3 N-terminal domain <br />
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**[[4lla]] – hLIR-2 ligand-binding domain D3D4 <br />
+
*LILRA5 subfamily A member 5
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**[[2otp]] – hLIR-2 ligand-binding domain D1D2 <br />
+
-
**[[6bcs]] – hLIR-2 ligand-binding domain D1D2 + benzamidine<br />
+
-
**[[6aed]] – hLIR-2 ligand-binding domain D1D2D3D4 (mutant)<br />
+
-
**[[2dyp]] – hLIR-2 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + H2A peptide<br />
+
-
*LIR-4
+
**[[2d3v]] – hLILRA5 extracerllular domain <br />
 +
**[[1vdg]] – hLILRA5 ligand-binding domain D1D2 (mutant) <br />
-
**[[3q2c]] – hLIR-4 N-terminal domain <br />
+
*LILRB1 subfamily B member 1
-
**[[6k7o]] – hLIR-4 N-terminal domain + antibody <br />
+
-
*LIR-5
+
**[[1g0x]] – hLILRB1 ligand-binding domain D1D2<br />
 +
**[[1ugn]] – hLILRB1 ligand-binding domain D1D2 (mutant) <br />
 +
**[[4ll9]] – hLILRB1 ligand-binding domain D3D4 <br />
 +
**[[7kfk]] – hLILRB1 ligand-binding domain D3D4 + Rifin<br />
 +
**[[6zdx]] – hLILRB1 ectodomain + Rifin<br />
 +
**[[1p7q]] – hLILRB1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + POL polyprotein peptide<br />
 +
**[[4no0]], [[5knm]], [[6aee]], [[6ewa]], [[6ewc]], [[6ewo]], [[6k60]] – hLILRB1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + peptide<br />
 +
**[[3d2u]] – hLILRB1 ligand-binding domain D1D2 + herpesvirus UL18 + β-2 microglobulin + actin peptide<br />
-
**[[3p2t]] – hLIR-5 ligand-binding domain D1D2 <br />
+
*LILRB2 subfamily B member 2
 +
 
 +
**[[4lla]] – hLILRB2 ligand-binding domain D3D4 <br />
 +
**[[6aed]] – hLILRB2 ligand-binding domain D1D2D3D4 (mutant)<br />
 +
**[[2gw5]] – hLILRB2 ligand-binding domain D1D2 <br />
 +
**[[6bcs]] – hLILRB2 ligand-binding domain D1D2 + benzamidine<br />
 +
**[[2dyp]] – hLILRB2 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + H2A peptide<br />
 +
 
 +
*LILRB3 subfamily B member 3
 +
 
 +
**[[6grq]], [[6grs]], [[6grt]] – mLILRB3 extracellular domain 25-619 <br />
 +
 
 +
*LILRB4 subfamily B member 4
 +
 
 +
**[[3p2t]] – hLILRB4 ligand-binding domain D1D2 <br />
 +
**[[6k7o]] – hLILRB4 N-terminal domain + antibody <br />
}}
}}

Revision as of 09:46, 17 October 2021

Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (salmon) complex with class I MHC (aqua), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry 1p7q)

Drag the structure with the mouse to rotate

3D structures of leukocyte immunoglobulin-like receptor

Updated on 17-October-2021

References

  1. ↑ Thomas R, Matthias T, Witte T. Leukocyte immunoglobulin-like receptors as new players in autoimmunity. Clin Rev Allergy Immunol. 2010 Apr;38(2-3):159-62. doi:, 10.1007/s12016-009-8148-8. PMID:19548123 doi:http://dx.doi.org/10.1007/s12016-009-8148-8

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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