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2jkg
From Proteopedia
(Difference between revisions)
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<StructureSection load='2jkg' size='340' side='right'caption='[[2jkg]], [[Resolution|resolution]] 1.89Å' scene=''> | <StructureSection load='2jkg' size='340' side='right'caption='[[2jkg]], [[Resolution|resolution]] 1.89Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2jkg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2jkg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JKG FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkg OCA], [https://pdbe.org/2jkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jkg RCSB], [https://www.ebi.ac.uk/pdbsum/2jkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkg ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkg OCA], [https://pdbe.org/2jkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jkg RCSB], [https://www.ebi.ac.uk/pdbsum/2jkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PROF_PLAF7 PROF_PLAF7] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers (By similarity).[UniProtKB:P86294] | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Plasmodium falciparum]] |
| - | [[Category: Ganter | + | [[Category: Synthetic construct]] |
| - | [[Category: Kursula | + | [[Category: Ganter M]] |
| - | [[Category: Kursula | + | [[Category: Kursula I]] |
| - | [[Category: Matuschewski | + | [[Category: Kursula P]] |
| - | [[Category: Panjikar | + | [[Category: Matuschewski K]] |
| - | [[Category: Schueler | + | [[Category: Panjikar S]] |
| - | + | [[Category: Schueler H]] | |
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Current revision
Plasmodium falciparum profilin
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