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2lll

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==Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A==
==Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A==
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<StructureSection load='2lll' size='340' side='right'caption='[[2lll]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2lll' size='340' side='right'caption='[[2lll]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2lll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2lll]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLL FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LMNB2, LMN2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lll OCA], [https://pdbe.org/2lll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lll RCSB], [https://www.ebi.ac.uk/pdbsum/2lll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lll ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lll FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lll OCA], [https://pdbe.org/2lll PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lll RCSB], [https://www.ebi.ac.uk/pdbsum/2lll PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lll ProSAT]</span></td></tr>
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</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN]] Partial acquired lipodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN] Partial acquired lipodystrophy. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN]] Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
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[https://www.uniprot.org/uniprot/LMNB2_HUMAN LMNB2_HUMAN] Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C]]
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[[Category: Arrowsmith C]]
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[[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]]
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[[Category: Garcia M]]
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[[Category: Garcia, M]]
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[[Category: Houliston S]]
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[[Category: Houliston, S]]
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[[Category: Lemak A]]
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[[Category: Lemak, A]]
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[[Category: Min J]]
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[[Category: Min, J]]
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[[Category: Montelione GT]]
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[[Category: Montelione, G T]]
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[[Category: Xu C]]
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[[Category: Structural genomic]]
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[[Category: Yee A]]
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[[Category: Xu, C]]
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[[Category: Yee, A]]
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[[Category: Ceb]]
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[[Category: Chaperone-enabled studies of epigenetic regulation enzyme]]
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[[Category: Immunoglobulin-like fold]]
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[[Category: Nesg]]
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[[Category: Psi-biology]]
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[[Category: Sgc]]
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[[Category: Structural protein]]
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Revision as of 11:06, 15 February 2023

Solution NMR structure of C-terminal globular domain of human Lamin-B2, Northeast Structural Genomics Consortium target HR8546A

PDB ID 2lll

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