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1u3i
From Proteopedia
(Difference between revisions)
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<StructureSection load='1u3i' size='340' side='right'caption='[[1u3i]], [[Resolution|resolution]] 1.89Å' scene=''> | <StructureSection load='1u3i' size='340' side='right'caption='[[1u3i]], [[Resolution|resolution]] 1.89Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1u3i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1u3i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U3I FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u3i OCA], [https://pdbe.org/1u3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u3i RCSB], [https://www.ebi.ac.uk/pdbsum/1u3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u3i ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u3i OCA], [https://pdbe.org/1u3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u3i RCSB], [https://www.ebi.ac.uk/pdbsum/1u3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u3i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/GST28_SCHMA GST28_SCHMA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Blood fluke]] | ||
| - | [[Category: Glutathione transferase]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Capron | + | [[Category: Schistosoma mansoni]] |
| - | [[Category: Chomilier | + | [[Category: Capron A]] |
| - | [[Category: Labesse | + | [[Category: Chomilier J]] |
| - | [[Category: Mormon | + | [[Category: Labesse G]] |
| - | [[Category: Trottein | + | [[Category: Mormon J-P]] |
| - | [[Category: Vaney | + | [[Category: Trottein F]] |
| - | + | [[Category: Vaney MC]] | |
| - | + | ||
Current revision
Crystal structure of glutathione S-tranferase from Schistosoma mansoni
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