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2m0o

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Current revision (13:22, 22 February 2023) (edit) (undo)
 
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==The solution structure of human PHF1 in complex with H3K36me3==
==The solution structure of human PHF1 in complex with H3K36me3==
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<StructureSection load='2m0o' size='340' side='right'caption='[[2m0o]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2m0o' size='340' side='right'caption='[[2m0o]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m0o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0O FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PHF1, PCL1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0o OCA], [https://pdbe.org/2m0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0o RCSB], [https://www.ebi.ac.uk/pdbsum/2m0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0o ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0o OCA], [https://pdbe.org/2m0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0o RCSB], [https://www.ebi.ac.uk/pdbsum/2m0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PHF1_HUMAN PHF1_HUMAN]] Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2/EED-EZH2 complex.<ref>PMID:18086877</ref> <ref>PMID:18285464</ref>
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[https://www.uniprot.org/uniprot/PHF1_HUMAN PHF1_HUMAN] Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2/EED-EZH2 complex.<ref>PMID:18086877</ref> <ref>PMID:18285464</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Patel, D J]]
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[[Category: Patel DJ]]
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[[Category: Song, J]]
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[[Category: Song J]]
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[[Category: H3k36me3 binding]]
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[[Category: Peptide binding protein]]
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[[Category: Tudor domain]]
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Current revision

The solution structure of human PHF1 in complex with H3K36me3

PDB ID 2m0o

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