2m0y
From Proteopedia
(Difference between revisions)
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==Solution structure of the SH3 domain of DOCK180== | ==Solution structure of the SH3 domain of DOCK180== | ||
| - | <StructureSection load='2m0y' size='340' side='right'caption='[[2m0y | + | <StructureSection load='2m0y' size='340' side='right'caption='[[2m0y]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2m0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0Y FirstGlance]. <br> |
| - | </td></tr> | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0y OCA], [https://pdbe.org/2m0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0y RCSB], [https://www.ebi.ac.uk/pdbsum/2m0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0y ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0y OCA], [https://pdbe.org/2m0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0y RCSB], [https://www.ebi.ac.uk/pdbsum/2m0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0y ProSAT]</span></td></tr> | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/DOCK1_MOUSE DOCK1_MOUSE] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity). | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Liu | + | [[Category: Liu X]] |
| - | [[Category: Wen | + | [[Category: Wen W]] |
| - | + | ||
Revision as of 13:23, 22 February 2023
Solution structure of the SH3 domain of DOCK180
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