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2m28

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==NMR structure of Ca2+ bound CaBP4 C-domain==
==NMR structure of Ca2+ bound CaBP4 C-domain==
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<StructureSection load='2m28' size='340' side='right'caption='[[2m28]], [[NMR_Ensembles_of_Models | 14 NMR models]]' scene=''>
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<StructureSection load='2m28' size='340' side='right'caption='[[2m28]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2m28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M28 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2m28]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M28 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M28 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2m29|2m29]]</div></td></tr>
 
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cabp4 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m28 OCA], [https://pdbe.org/2m28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m28 RCSB], [https://www.ebi.ac.uk/pdbsum/2m28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m28 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m28 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m28 OCA], [https://pdbe.org/2m28 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m28 RCSB], [https://www.ebi.ac.uk/pdbsum/2m28 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m28 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CABP4_MOUSE CABP4_MOUSE]] Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.<ref>PMID:15452577</ref> <ref>PMID:16249514</ref> <ref>PMID:17050707</ref> <ref>PMID:17947313</ref>
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[https://www.uniprot.org/uniprot/CABP4_MOUSE CABP4_MOUSE] Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.<ref>PMID:15452577</ref> <ref>PMID:16249514</ref> <ref>PMID:17050707</ref> <ref>PMID:17947313</ref>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Ames, J B]]
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[[Category: Ames JB]]
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[[Category: Metal binding protein]]
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Revision as of 13:25, 22 February 2023

NMR structure of Ca2+ bound CaBP4 C-domain

PDB ID 2m28

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