7kh0
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | ==== | + | ==Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex== |
| - | <StructureSection load='7kh0' size='340' side='right'caption='[[7kh0]]' scene=''> | + | <StructureSection load='7kh0' size='340' side='right'caption='[[7kh0]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7kh0]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KH0 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kh0 OCA], [https://pdbe.org/7kh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kh0 RCSB], [https://www.ebi.ac.uk/pdbsum/7kh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kh0 ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kh0 OCA], [https://pdbe.org/7kh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kh0 RCSB], [https://www.ebi.ac.uk/pdbsum/7kh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kh0 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/V2R_HUMAN V2R_HUMAN] Nephrogenic syndrome of inappropriate antidiuresis;Inappropriate antidiuretic hormone secretion syndrome;Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/V2R_HUMAN V2R_HUMAN] Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.<ref>PMID:19440390</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Transducin 3D structures|Transducin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Lama glama]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Z | + | [[Category: Du Y]] |
| + | [[Category: Gao S]] | ||
| + | [[Category: Liu H]] | ||
| + | [[Category: Liu Z]] | ||
| + | [[Category: Sun D]] | ||
| + | [[Category: Wang L]] | ||
| + | [[Category: Xu J]] | ||
| + | [[Category: Zhang C]] | ||
Revision as of 07:00, 29 March 2023
Cryo-EM structure of the human arginine vasopressin AVP-vasopressin receptor V2R-Gs signaling complex
| |||||||||||
Categories: Homo sapiens | Lama glama | Large Structures | Du Y | Gao S | Liu H | Liu Z | Sun D | Wang L | Xu J | Zhang C
