1ehv

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[[Image:1ehv.gif|left|200px]]
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{{Seed}}
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{{STRUCTURE_1ehv| PDB=1ehv | SCENE= }}
{{STRUCTURE_1ehv| PDB=1ehv | SCENE= }}
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'''A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE'''
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===A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE===
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==Overview==
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The dodecanucleotide d(CGCGAATTCGCG) has been crystallised in the space group P3(2)12, representing a new crystal form for this sequence. The structure has been solved by molecular replacement and refined at 1.8 A resolution. The present structure contrasts with previous ones for this sequence since it is situated on a crystallographic 2-fold axis, and the crystal symmetry reflects the palindromic nature of this sequence. Some features accord with previous observations, notably that the minor groove is hydrated with a continuous spine of solvent. There is no evidence of alkali metal ions within this spine. The minor groove retains its narrow width, although it is now symmetric and extends over the A/T tract. Various base and base-pair morphological parameters have been examined. Their values do not show significant correlations with earlier reports, suggesting that crystal packing effects on them are more dominant than has been hitherto realised.
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(as it appears on PubMed at http://www.pubmed.gov), where 10884351 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10884351}}
==About this Structure==
==About this Structure==
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[[Category: Dickerson dodecamer]]
[[Category: Dickerson dodecamer]]
[[Category: Dna]]
[[Category: Dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:07:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:43:04 2008''

Revision as of 21:43, 30 June 2008

Image:1ehv.png

Template:STRUCTURE 1ehv

A NEW CRYSTAL STRUCTURE FOR THE DODECAMER C-G-C-G-A-A-T-T-C-G-C-G: SYMMETRY EFFECTS ON SEQUENCE-DEPENDENT DNA STRUCTURE

Template:ABSTRACT PUBMED 10884351

About this Structure

Full crystallographic information is available from OCA.

Reference

A new crystal form for the dodecamer C-G-C-G-A-A-T-T-C-G-C-G: symmetry effects on sequence-dependent DNA structure., Johansson E, Parkinson G, Neidle S, J Mol Biol. 2000 Jul 14;300(3):551-61. PMID:10884351

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