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1ala
From Proteopedia
(Difference between revisions)
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<StructureSection load='1ala' size='340' side='right'caption='[[1ala]], [[Resolution|resolution]] 2.25Å' scene=''> | <StructureSection load='1ala' size='340' side='right'caption='[[1ala]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1ala]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1ala]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ALA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ALA FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ala FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ala OCA], [https://pdbe.org/1ala PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ala RCSB], [https://www.ebi.ac.uk/pdbsum/1ala PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ala ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ala FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ala OCA], [https://pdbe.org/1ala PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ala RCSB], [https://www.ebi.ac.uk/pdbsum/1ala PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ala ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/ANXA5_CHICK ANXA5_CHICK] Collagen-binding protein. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ala ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ala ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The crystal structure of chicken annexin V has been solved by molecular replacement and refined at 2.25 A. The final R factor is 19.7% with good geometry. The chicken annexin V structure is very similar to the human annexin V structure, with four similar domains each containing five helices. The structure includes three calcium ions in domains I, II, and IV, each bound by the characteristic K-G-X-G-T-(38 residues)-D/E motif. In view of the structural similarity between human and chicken annexin V, we suggest that they have a common vital function which developed early in evolutionary history. | ||
| - | |||
| - | Structure of chicken annexin V at 2.25-A resolution.,Bewley MC, Boustead CM, Walker JH, Waller DA, Huber R Biochemistry. 1993 Apr 20;32(15):3923-9. PMID:8471604<ref>PMID:8471604</ref> | ||
| - | |||
| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1ala" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Annexin 3D structures|Annexin 3D structures]] | *[[Annexin 3D structures|Annexin 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Gallus gallus]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bewley | + | [[Category: Bewley MC]] |
| - | [[Category: Huber | + | [[Category: Huber R]] |
| - | [[Category: Waller | + | [[Category: Waller DA]] |
| - | + | ||
| - | + | ||
Current revision
STRUCTURE OF CHICKEN ANNEXIN V AT 2.25-ANGSTROMS RESOLUTION
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