7clr
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==CryoEM structure of S.typhimurium flagellar LP ring== |
| - | <StructureSection load='7clr' size='340' side='right'caption='[[7clr]]' scene=''> | + | <StructureSection load='7clr' size='340' side='right'caption='[[7clr]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7clr]] is a 52 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CLR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CLR FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7clr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7clr OCA], [https://pdbe.org/7clr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7clr RCSB], [https://www.ebi.ac.uk/pdbsum/7clr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7clr ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7clr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7clr OCA], [https://pdbe.org/7clr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7clr RCSB], [https://www.ebi.ac.uk/pdbsum/7clr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7clr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FLGI_SALTY FLGI_SALTY] Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The basal body of the bacterial flagellum is a rotary motor that consists of several rings (C, MS and LP) and a rod. The LP ring acts as a bushing supporting the distal rod for its rapid and stable rotation without much friction. Here, we use electron cryomicroscopy to describe the LP ring structure around the rod, at 3.5 A resolution, from Salmonella Typhimurium. The structure shows 26-fold rotational symmetry and intricate intersubunit interactions of each subunit with up to six partners, which explains the structural stability. The inner surface is charged both positively and negatively. Positive charges on the P ring (the part of the LP ring that is embedded within the peptidoglycan layer) presumably play important roles in its initial assembly around the rod with a negatively charged surface. | ||
| + | |||
| + | Structure of the molecular bushing of the bacterial flagellar motor.,Yamaguchi T, Makino F, Miyata T, Minamino T, Kato T, Namba K Nat Commun. 2021 Jul 22;12(1):4469. doi: 10.1038/s41467-021-24715-3. PMID:34294704<ref>PMID:34294704</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 7clr" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| + | [[Category: Kato T]] | ||
| + | [[Category: Makino F]] | ||
| + | [[Category: Minamino T]] | ||
| + | [[Category: Miyata T]] | ||
| + | [[Category: Namba K]] | ||
| + | [[Category: Yamaguchi T]] | ||
Current revision
CryoEM structure of S.typhimurium flagellar LP ring
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