2opg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:46, 30 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2opg' size='340' side='right'caption='[[2opg]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='2opg' size='340' side='right'caption='[[2opg]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2opg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OPG FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2opg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OPG FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MPDZ, MUPP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2opg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opg OCA], [https://pdbe.org/2opg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2opg RCSB], [https://www.ebi.ac.uk/pdbsum/2opg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2opg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2opg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opg OCA], [https://pdbe.org/2opg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2opg RCSB], [https://www.ebi.ac.uk/pdbsum/2opg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2opg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/MPDZ_HUMAN MPDZ_HUMAN]] Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref>
+
[https://www.uniprot.org/uniprot/MPDZ_HUMAN MPDZ_HUMAN] Interacts with HTR2C and provokes its clustering at the cell surface (By similarity). Member of the NMDAR signaling complex that may play a role in control of AMPAR potentiation and synaptic plasticity in excitatory synapses.<ref>PMID:11150294</ref> <ref>PMID:15312654</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 24: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berridge, G]]
+
[[Category: Berridge G]]
-
[[Category: Doyle, D A]]
+
[[Category: Doyle DA]]
-
[[Category: Edwards, A]]
+
[[Category: Edwards A]]
-
[[Category: Elkins, J]]
+
[[Category: Elkins J]]
-
[[Category: Gileadi, C]]
+
[[Category: Gileadi C]]
-
[[Category: Gileadi, O]]
+
[[Category: Gileadi O]]
-
[[Category: Gorrec, F]]
+
[[Category: Gorrec F]]
-
[[Category: Papagrigoriou, E]]
+
[[Category: Papagrigoriou E]]
-
[[Category: Phillips, C]]
+
[[Category: Phillips C]]
-
[[Category: Structural genomic]]
+
[[Category: Salah E]]
-
[[Category: Salah, E]]
+
[[Category: Savitsky P]]
-
[[Category: Savitsky, P]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M]]
+
[[Category: Ugochukwu E]]
-
[[Category: Ugochukwu, E]]
+
[[Category: Umeano C]]
-
[[Category: Umeano, C]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural protein]]
+

Current revision

The crystal structure of the 10th PDZ domain of MPDZ

PDB ID 2opg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2opg"
Personal tools