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2oqk

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Current revision (00:22, 28 December 2023) (edit) (undo)
 
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<StructureSection load='2oqk' size='340' side='right'caption='[[2oqk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2oqk' size='340' side='right'caption='[[2oqk]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2oqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Crypi Crypi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2oqk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum_Iowa_II Cryptosporidium parvum Iowa II]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cgd8_3330 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353152 CRYPI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqk OCA], [https://pdbe.org/2oqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqk RCSB], [https://www.ebi.ac.uk/pdbsum/2oqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqk OCA], [https://pdbe.org/2oqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqk RCSB], [https://www.ebi.ac.uk/pdbsum/2oqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q5CVP1_CRYPI Q5CVP1_CRYPI]] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.[RuleBase:RU004365]
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[https://www.uniprot.org/uniprot/Q5CVP1_CRYPI Q5CVP1_CRYPI] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.[RuleBase:RU004365]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Crypi]]
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[[Category: Cryptosporidium parvum Iowa II]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Altamentova, S]]
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[[Category: Altamentova S]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bochkarev, A]]
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[[Category: Bochkarev A]]
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[[Category: Brokx, S J]]
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[[Category: Brokx SJ]]
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[[Category: Dong, A]]
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[[Category: Dong A]]
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[[Category: Edwards, A M]]
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[[Category: Edwards AM]]
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[[Category: Hassanali, A]]
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[[Category: Hassanali A]]
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[[Category: Hui, R]]
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[[Category: Hui R]]
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[[Category: Kozieradzki, I]]
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[[Category: Kozieradzki I]]
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[[Category: Lew, J]]
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[[Category: Lew J]]
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[[Category: Lin, L]]
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[[Category: Lin L]]
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[[Category: Qiu, W]]
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[[Category: Qiu W]]
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[[Category: Structural genomic]]
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[[Category: Sundstrom M]]
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[[Category: Sundstrom, M]]
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[[Category: Vedadi M]]
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[[Category: Vedadi, M]]
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[[Category: Wasney G]]
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[[Category: Wasney, G]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Zhao Y]]
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[[Category: Zhao, Y]]
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[[Category: Cryptosporidium parvum]]
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[[Category: Malaria]]
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[[Category: Sgc]]
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[[Category: Translation]]
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Current revision

Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A

PDB ID 2oqk

Drag the structure with the mouse to rotate

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