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7dog

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Current revision (16:37, 29 November 2023) (edit) (undo)
 
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<StructureSection load='7dog' size='340' side='right'caption='[[7dog]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
<StructureSection load='7dog' size='340' side='right'caption='[[7dog]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7dog]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7dog]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DOG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sbcD, SAV1345 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dog OCA], [https://pdbe.org/7dog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dog RCSB], [https://www.ebi.ac.uk/pdbsum/7dog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dog ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dog OCA], [https://pdbe.org/7dog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dog RCSB], [https://www.ebi.ac.uk/pdbsum/7dog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dog ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SBCD_STAAM SBCD_STAAM]] SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity).
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[https://www.uniprot.org/uniprot/SBCD_STAAM SBCD_STAAM] SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staam]]
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[[Category: Staphylococcus aureus subsp. aureus Mu50]]
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[[Category: Ha, N C]]
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[[Category: Ha N-C]]
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[[Category: Lee, J]]
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[[Category: Lee J]]
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[[Category: Dna nuclease]]
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[[Category: Dna repair]]
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[[Category: Endonuclease]]
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[[Category: Exonuclease]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of a nuclease and capping domain of SbcD from Staphylococcus aureus

PDB ID 7dog

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