7eki

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Current revision (11:00, 23 October 2024) (edit) (undo)
 
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<StructureSection load='7eki' size='340' side='right'caption='[[7eki]], [[Resolution|resolution]] 3.18&Aring;' scene=''>
<StructureSection load='7eki' size='340' side='right'caption='[[7eki]], [[Resolution|resolution]] 3.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7eki]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EKI FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EKI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EKI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.18&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CHRNA7, NACHRA7 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7eki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7eki OCA], [https://pdbe.org/7eki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7eki RCSB], [https://www.ebi.ac.uk/pdbsum/7eki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7eki ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7eki FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7eki OCA], [https://pdbe.org/7eki PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7eki RCSB], [https://www.ebi.ac.uk/pdbsum/7eki PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7eki ProSAT]</span></td></tr>
</table>
</table>
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== Disease ==
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[[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN]] 15q13.3 microdeletion syndrome.
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==See Also==
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== Function ==
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*[[Acetyl choline receptor 3D structures|Acetyl choline receptor 3D structures]]
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[[https://www.uniprot.org/uniprot/ACHA7_HUMAN ACHA7_HUMAN]] After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by alpha-bungarotoxin.
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Liu, S]]
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[[Category: Liu S]]
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[[Category: Sun, D]]
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[[Category: Sun D]]
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[[Category: Tian, C]]
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[[Category: Tian C]]
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[[Category: Zhao, Y]]
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[[Category: Zhao Y]]
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[[Category: Alpha 7]]
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[[Category: Apo-form]]
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[[Category: Membrane protein]]
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[[Category: Nicotinic acetylcholine receptor]]
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Current revision

human alpha 7 nicotinic acetylcholine receptor in apo-form

PDB ID 7eki

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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