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2p59
From Proteopedia
(Difference between revisions)
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<StructureSection load='2p59' size='340' side='right'caption='[[2p59]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='2p59' size='340' side='right'caption='[[2p59]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2p59]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2p59]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C] and [https://en.wikipedia.org/wiki/Hepatitis_C_virus_(isolate_H) Hepatitis C virus (isolate H)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P59 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P59 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GG4:(2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE'>GG4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GG4:(2S,3AS,7AS)-1-[(2S)-2-{[(2S)-2-CYCLOHEXYL-2-({[(2R)-4-NITRO-2H-PYRROL-2-YL]CARBONYL}AMINO)ACETYL]AMINO}-3,3-DIMETHYLBUTANOYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]BUTYL}OCTAHYDRO-1H-INDOLE-2-CARBOXAMIDE'>GG4</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 protease domain ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11103 9HEPC])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p59 OCA], [https://pdbe.org/2p59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p59 RCSB], [https://www.ebi.ac.uk/pdbsum/2p59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p59 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p59 OCA], [https://pdbe.org/2p59 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p59 RCSB], [https://www.ebi.ac.uk/pdbsum/2p59 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p59 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q91RS4_9HEPC Q91RS4_9HEPC] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Hepacivirus C]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Perni | + | [[Category: Perni RB]] |
| - | [[Category: Wei | + | [[Category: Wei Y]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Hepatitis C Virus NS3.4A protease
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