2p86
From Proteopedia
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<StructureSection load='2p86' size='340' side='right'caption='[[2p86]], [[Resolution|resolution]] 1.16Å' scene=''> | <StructureSection load='2p86' size='340' side='right'caption='[[2p86]], [[Resolution|resolution]] 1.16Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2p86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2p86]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_rhodesiense Trypanosoma brucei rhodesiense]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P86 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=VS1:3-[[N-[MORPHOLIN-N-YL]-CARBONYL]-PHENYLALANINYL-AMINO]-5-+PHENYL-PENTANE-1-SULFONYLBENZENE'>VS1</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p86 OCA], [https://pdbe.org/2p86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p86 RCSB], [https://www.ebi.ac.uk/pdbsum/2p86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p86 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p86 OCA], [https://pdbe.org/2p86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p86 RCSB], [https://www.ebi.ac.uk/pdbsum/2p86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p86 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q95PM0_TRYBR Q95PM0_TRYBR] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cathepsin L]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Trypanosoma brucei rhodesiense]] |
| - | [[Category: Brinen | + | [[Category: Brinen LS]] |
| - | [[Category: Marion | + | [[Category: Marion R]] |
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Current revision
The high resolution crystal structure of rhodesain, the major cathepsin L protease from T. brucei rhodesiense, bound to inhibitor K11002
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