2pnv
From Proteopedia
(Difference between revisions)
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<StructureSection load='2pnv' size='340' side='right'caption='[[2pnv]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='2pnv' size='340' side='right'caption='[[2pnv]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2pnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2pnv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PNV FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pnv OCA], [https://pdbe.org/2pnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pnv RCSB], [https://www.ebi.ac.uk/pdbsum/2pnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pnv ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pnv OCA], [https://pdbe.org/2pnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pnv RCSB], [https://www.ebi.ac.uk/pdbsum/2pnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pnv ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/KCNN2_RAT KCNN2_RAT] Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Buffalo rat]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Eom, S H]] | ||
| - | [[Category: Kang, G B]] | ||
| - | [[Category: Kim, J Y]] | ||
| - | [[Category: Kim, M K]] | ||
| - | [[Category: Park, C S]] | ||
| - | [[Category: Leucine zipper]] | ||
| - | [[Category: Membrane protein]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: | + | [[Category: Eom SH]] |
| + | [[Category: Kang GB]] | ||
| + | [[Category: Kim JY]] | ||
| + | [[Category: Kim MK]] | ||
| + | [[Category: Park CS]] | ||
Current revision
Crystal Structure of the leucine zipper domain of small-conductance Ca2+-activated K+ (SKCa) channel from Rattus norvegicus
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Categories: Large Structures | Rattus norvegicus | Eom SH | Kang GB | Kim JY | Kim MK | Park CS
