This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1eo6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1eo6.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1eo6.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1eo6| PDB=1eo6 | SCENE= }}
{{STRUCTURE_1eo6| PDB=1eo6 | SCENE= }}
-
'''CRYSTAL STRUCTURE OF GATE-16'''
+
===CRYSTAL STRUCTURE OF GATE-16===
-
==Overview==
+
<!--
-
The GATE-16 protein participates in intra-Golgi transport and can associate with the N-ethylmaleimide-sensitive fusion protein and with Golgi SNAREs. The yeast ortholog of GATE-16 is the autophagocytosis factor Aut7p. GATE-16 is also closely related to the GABA receptor-associated protein (GABARAP), which has been proposed to cluster neurotransmitter receptors by mediating interaction with the cytoskeleton, and to the light chain-3 subunit of the neuronal microtubule-associated protein complex. Here, we present the crystal structure of GATE-16 refined to 1.8 A resolution. GATE-16 contains a ubiquitin fold decorated by two additional N-terminal helices. Proteins with strong structural similarity but no detectable sequence homology to GATE-16 include Ras effectors that mediate diverse downstream functions, but each interacts with Ras by forming pseudo-continuous beta-sheets. The GATE-16 surface suggests that it binds its targets in a similar manner. Moreover, a second potential protein-protein interaction site on GATE-16 may explain the adapter activity observed for members of the GATE-16 family.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10856287}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10856287 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10856287}}
==About this Structure==
==About this Structure==
Line 26: Line 30:
[[Category: Paz, Y.]]
[[Category: Paz, Y.]]
[[Category: Ubiquitin fold]]
[[Category: Ubiquitin fold]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:20:12 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:15:41 2008''

Revision as of 22:15, 30 June 2008

Image:1eo6.png

Template:STRUCTURE 1eo6

CRYSTAL STRUCTURE OF GATE-16

Template:ABSTRACT PUBMED 10856287

About this Structure

1EO6 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p., Paz Y, Elazar Z, Fass D, J Biol Chem. 2000 Aug 18;275(33):25445-50. PMID:10856287

Page seeded by OCA on Tue Jul 1 01:15:41 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1eo6"
Personal tools