2q1e

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<StructureSection load='2q1e' size='340' side='right'caption='[[2q1e]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='2q1e' size='340' side='right'caption='[[2q1e]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2q1e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q1E FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2q1e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q1E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q1E FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mutant of Vk1 O18/O8 germline ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q1e OCA], [https://pdbe.org/2q1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q1e RCSB], [https://www.ebi.ac.uk/pdbsum/2q1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q1e ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q1e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q1e OCA], [https://pdbe.org/2q1e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q1e RCSB], [https://www.ebi.ac.uk/pdbsum/2q1e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q1e ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A2NI60_HUMAN A2NI60_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Baden, E M]]
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[[Category: Baden EM]]
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[[Category: Ramirez-Alvarado, M]]
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[[Category: Ramirez-Alvarado M]]
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[[Category: Thompson, J R]]
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[[Category: Thompson JR]]
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[[Category: Al]]
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[[Category: Amyloid]]
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[[Category: Immunoglobulin]]
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[[Category: Light chain]]
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[[Category: Light chain amyloidosis]]
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[[Category: Light chain variable domain]]
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[[Category: Protein fibril]]
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Revision as of 07:18, 29 March 2023

Altered dimer interface decreases stability in an amyloidogenic kappa1 Bence Jones protein.

PDB ID 2q1e

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OCA

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