This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2qdt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:29, 30 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2qdt' size='340' side='right'caption='[[2qdt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='2qdt' size='340' side='right'caption='[[2qdt]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2qdt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"pseudomonas_maltophilia"_hugh_and_ryschenkow_1961 "pseudomonas maltophilia" hugh and ryschenkow 1961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDT FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2qdt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Stenotrophomonas_maltophilia Stenotrophomonas maltophilia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QDT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QDT FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I38:N-(3-MERCAPTOPROPANOYL)-D-ALANINE'>I38</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2fm6|2fm6]], [[2gkl|2gkl]], [[2fu9|2fu9]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I38:N-(3-MERCAPTOPROPANOYL)-D-ALANINE'>I38</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">L1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=40324 "Pseudomonas maltophilia" Hugh and Ryschenkow 1961])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdt OCA], [https://pdbe.org/2qdt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qdt RCSB], [https://www.ebi.ac.uk/pdbsum/2qdt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qdt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qdt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qdt OCA], [https://pdbe.org/2qdt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qdt RCSB], [https://www.ebi.ac.uk/pdbsum/2qdt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qdt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/BLA1_STEMA BLA1_STEMA]] Has a high activity against imipenem.
+
[https://www.uniprot.org/uniprot/BLA1_STEMA BLA1_STEMA] Has a high activity against imipenem.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 39: Line 37:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Pseudomonas maltophilia hugh and ryschenkow 1961]]
 
-
[[Category: Beta-lactamase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Dideberg, O]]
+
[[Category: Stenotrophomonas maltophilia]]
-
[[Category: Garau, G]]
+
[[Category: Dideberg O]]
-
[[Category: Hydrolase]]
+
[[Category: Garau G]]
-
[[Category: Inhibitor]]
+
-
[[Category: L1]]
+
-
[[Category: Lactamase]]
+
-
[[Category: Metallo]]
+
-
[[Category: Zn]]
+

Current revision

Structural Basis for the Broad-Spectrum Inhibition of Metallo-{Beta}-Lactamases: L1- IS38 Complex

PDB ID 2qdt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools