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DNA glycosylase 3D structures
From Proteopedia
(Difference between revisions)
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{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | *Adenine DG | + | *Adenine DG or MutY |
**[[3n5n]] – hADG catalytic domain – human<BR /> | **[[3n5n]] – hADG catalytic domain – human<BR /> | ||
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**[[6q0c]], [[6u7t]] - GsADG + DNA – ''Geobacillus stearothermophilus''<br /> | **[[6q0c]], [[6u7t]] - GsADG + DNA – ''Geobacillus stearothermophilus''<br /> | ||
**[[6q0c]], [[6u7t]] – GsADG + DNA <BR /> | **[[6q0c]], [[6u7t]] – GsADG + DNA <BR /> | ||
| - | **[[3g0q]], [[1vrl]], [[1rrq]], [[1rrs]], [[5kn8]] - GsADG (mutant) + DNA <BR /> | + | **[[3g0q]], [[1vrl]], [[1rrq]], [[1rrs]], [[5kn8]], [[8dvy]], [[8dw0]], [[8dw4]], [[8dw7]] - GsADG (mutant) + DNA <BR /> |
| - | **[[6u7t]], [[5kn9]] – GsADG + DNA with oxo-guanine<br /> | + | **[[6u7t]], [[5kn9]], [[8dvp]] – GsADG + DNA with oxo-guanine<br /> |
*A/G specific adenine DG complex | *A/G specific adenine DG complex | ||
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*Uracil-DNA glycosylase complex with uracil derivatives | *Uracil-DNA glycosylase complex with uracil derivatives | ||
| - | **[[5eug]], [[2eug]], [[1flz]] – EcUDG (mutant) + uracil<br /> | + | **[[5eug]], [[2eug]], [[1flz]] , [[3eug]]– EcUDG (mutant) + uracil<br /> |
**[[1ui0]] – TtUDG + Fe4S4 + uracil <br /> | **[[1ui0]] – TtUDG + Fe4S4 + uracil <br /> | ||
**[[4lzb]] – VvUDG (mutant) + uracil<br /> | **[[4lzb]] – VvUDG (mutant) + uracil<br /> | ||
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**[[2hxm]], [[3fcf]], [[3fci]], [[3fck]], [[3fcl]], [[6vba]] – hUDG + inhibitor<br /> | **[[2hxm]], [[3fcf]], [[3fci]], [[3fck]], [[3fcl]], [[6vba]] – hUDG + inhibitor<br /> | ||
**[[5jk7]] – hUDG + DNA damage-binding protein + VPRBP + VPR <br /> | **[[5jk7]] – hUDG + DNA damage-binding protein + VPRBP + VPR <br /> | ||
| + | **[[7v7c]] – hUDG + DNA damage-binding protein + VPRBP + VPR – Cryo EM<br /> | ||
**[[5ayr]], [[5ays]] – hUDG + protein<br /> | **[[5ayr]], [[5ays]] – hUDG + protein<br /> | ||
**[[3uf7]] – EcUDG + single-stranded DNA-binding protein C terminal<br /> | **[[3uf7]] – EcUDG + single-stranded DNA-binding protein C terminal<br /> | ||
**[[3ufm]] – DrUDG + single-stranded DNA-binding protein C terminal<br /> | **[[3ufm]] – DrUDG + single-stranded DNA-binding protein C terminal<br /> | ||
**[[3zoq]] – BsUDG + p56 <br /> | **[[3zoq]] – BsUDG + p56 <br /> | ||
| + | **[[5gn2]], [[5gn3]] – BdUDG – ''Bradyrhizobium diazoefficiens'' <br /> | ||
| + | **[[5grk]] – BdUDG + xanthine <br /> | ||
| + | **[[5gnw]] – BdUDG + uracil <br /> | ||
**[[4od8]], [[4oda]], [[4ygm]], [[5jkr]] – VvUDG + DNA polymerase processivity factor component A20 N terminal<br /> | **[[4od8]], [[4oda]], [[4ygm]], [[5jkr]] – VvUDG + DNA polymerase processivity factor component A20 N terminal<br /> | ||
**[[5jks]], [[5jkt]] – VvUDG (mutant) + DNA polymerase processivity factor component A20 N terminal<br /> | **[[5jks]], [[5jkt]] – VvUDG (mutant) + DNA polymerase processivity factor component A20 N terminal<br /> | ||
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**[[2nob]], [[2noe]], [[2nof]], [[2noh]], [[2noi]], [[2nol]], [[2noz]], [[2i5w]], [[1yqk]], [[1yql]], [[1yqm]], [[1yqr]], [[1n39]], [[1n3a]], [[1n3c]] - hOgg1 (mutant) + DNA<BR /> | **[[2nob]], [[2noe]], [[2nof]], [[2noh]], [[2noi]], [[2nol]], [[2noz]], [[2i5w]], [[1yqk]], [[1yql]], [[1yqm]], [[1yqr]], [[1n39]], [[1n3a]], [[1n3c]] - hOgg1 (mutant) + DNA<BR /> | ||
**[[6rlw]] - hOgg1 + inhibitor<br /> | **[[6rlw]] - hOgg1 + inhibitor<br /> | ||
| + | **[[7cfa]] - hOgg1 + activator<br /> | ||
**[[1lwv]], [[1lww]], [[1lwy]] - hOgg1 + DNA<BR /> + guanine derivative<BR /> | **[[1lwv]], [[1lww]], [[1lwy]] - hOgg1 + DNA<BR /> + guanine derivative<BR /> | ||
**[[1m3h]], [[3ih7]] - hOgg1 core fragment (mutant) + DNA<BR /> | **[[1m3h]], [[3ih7]] - hOgg1 core fragment (mutant) + DNA<BR /> | ||
**[[1m3q]], [[1ebm]] - hOgg1 core fragment (mutant) + DNA + guanine derivative | **[[1m3q]], [[1ebm]] - hOgg1 core fragment (mutant) + DNA + guanine derivative | ||
| - | *8-oxoguanine (oxoG) DG | + | *8-oxoguanine (oxoG) DG or N-glycosylase/DNA ligase |
**[[6g3x]] – mOgg1 – mouse<br /> | **[[6g3x]] – mOgg1 – mouse<br /> | ||
| - | **[[6g40]], [[6g3y]] – mOgg1 + inhibitor<br /> | + | **[[6g40]], [[6g3y]], [[7pz1]], [[7qel]] – mOgg1 + inhibitor<br /> |
| + | **[[7ayz]], [[7az0]] - mOgg1 + activator<br /> | ||
**[[3n0u]] – TmOxDG<BR /> | **[[3n0u]] – TmOxDG<BR /> | ||
**[[3knt]] - MjOxDG (mutant) + DNA – ''Methanocaldococcus jannaschii''<BR /> | **[[3knt]] - MjOxDG (mutant) + DNA – ''Methanocaldococcus jannaschii''<BR /> | ||
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**[[4ejy]], [[4ejz]] – OxDG + DNA – ''Thermoanaerobacter tengcongensis''<br /> | **[[4ejy]], [[4ejz]] – OxDG + DNA – ''Thermoanaerobacter tengcongensis''<br /> | ||
**[[4pii]] – OxDG – ''Pyrococcus furiosus''<br /> | **[[4pii]] – OxDG – ''Pyrococcus furiosus''<br /> | ||
| + | **[[7ou3]] – OxDG – ''Thermococcus gammatolerans''<br /> | ||
| + | **[[7olb]], [[7oli]] – PaOxDG – ''Pyrococcus abyssi''<br /> | ||
| + | **[[7oue]], [[7oy7]], [[7p0w]], [[7p8l]], [[7p9z]] – PaOxDG + DNA <br /> | ||
*Methyladenine DG | *Methyladenine DG | ||
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**[[1pu6]] – HpAlkDG – ''Helicobacter pylori''<BR /> | **[[1pu6]] – HpAlkDG – ''Helicobacter pylori''<BR /> | ||
**[[4ai4]] – SaAlkDG (mutant)<br /> | **[[4ai4]] – SaAlkDG (mutant)<br /> | ||
| + | **[[2yg8]] – DrAlkDG<br /> | ||
*Methyladenine DG complex | *Methyladenine DG complex | ||
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**[[3qi5]], [[1ewn]], [[1f4r]], [[1f6o]], [[1bnk]], [[3uby]] – hAlkDG + DNA<BR /> | **[[3qi5]], [[1ewn]], [[1f4r]], [[1f6o]], [[1bnk]], [[3uby]] – hAlkDG + DNA<BR /> | ||
**[[3jx7]], [[3jxy]], [[3jxz]], [[3jy1]] - BcAlkDG + DNA<BR /> | **[[3jx7]], [[3jxy]], [[3jxz]], [[3jy1]] - BcAlkDG + DNA<BR /> | ||
| + | **[[7lxh]], [[7lxj]] - BcAlkDG + DNA + ribose derivative + inhibitor<br /> | ||
**[[5uuh]], [[5uug]], [[5uuf]], [[5kub]] – BcAlkDG + damaged DNA <br /> | **[[5uuh]], [[5uug]], [[5uuf]], [[5kub]] – BcAlkDG + damaged DNA <br /> | ||
**[[3ogd]], [[3oh6]], [[3oh9]] - EcAlkDG (mutant) + DNA<BR /> | **[[3ogd]], [[3oh6]], [[3oh9]] - EcAlkDG (mutant) + DNA<BR /> | ||
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**[[5vi0]] – PfAlkCDG + DNA – ''Pseudomonas fluorescens''<br /> | **[[5vi0]] – PfAlkCDG + DNA – ''Pseudomonas fluorescens''<br /> | ||
**[[5vhv]] – PfAlkCDG + damaged DNA <br /> | **[[5vhv]] – PfAlkCDG + damaged DNA <br /> | ||
| + | **[[5cl3]], [[5cl4]], [[5cl5]], [[5cl6]], [[5cl7]], [[5cl8]], [[5cl9]], [[5cla]], [[5clb]], [[5clc]], [[5cld]], [[5cle]] – BcAlkCDG + DNA <br /> | ||
*Formamidopyrimidine DG | *Formamidopyrimidine DG | ||
Current revision
3D Structures of DNA glycosylase
Updated on 31-January-2023
