2qvh
From Proteopedia
(Difference between revisions)
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==Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)== | ==Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)== | ||
| - | <StructureSection load='2qvh' size='340' side='right'caption='[[2qvh]]' scene=''> | + | <StructureSection load='2qvh' size='340' side='right'caption='[[2qvh]], [[Resolution|resolution]] 1.76Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[2qvh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca_YX Thermobifida fusca YX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QVH FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvh OCA], [https://pdbe.org/2qvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvh RCSB], [https://www.ebi.ac.uk/pdbsum/2qvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2qvh TOPSAN]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OSB:2-SUCCINYLBENZOATE'>OSB</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qvh OCA], [https://pdbe.org/2qvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qvh RCSB], [https://www.ebi.ac.uk/pdbsum/2qvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qvh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2qvh TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MENC_THEFY MENC_THEFY] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444). Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substrate (PubMed:24872444).<ref>PMID:24060347</ref> <ref>PMID:24872444</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qvh ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qvh ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Thermobifida fusca YX]] | ||
[[Category: Burley SK]] | [[Category: Burley SK]] | ||
[[Category: Sugadev R]] | [[Category: Sugadev R]] | ||
[[Category: Swaminathan S]] | [[Category: Swaminathan S]] | ||
Revision as of 11:41, 30 August 2023
Crystal structure of O-succinylbenzoate synthase complexed with O-succinyl benzoate (OSB)
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