This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2r2q

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:44, 30 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='2r2q' size='340' side='right'caption='[[2r2q]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2r2q' size='340' side='right'caption='[[2r2q]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2r2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R2Q FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2r2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R2Q FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GABARAPL1, GEC1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2q OCA], [https://pdbe.org/2r2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r2q RCSB], [https://www.ebi.ac.uk/pdbsum/2r2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r2q ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r2q OCA], [https://pdbe.org/2r2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r2q RCSB], [https://www.ebi.ac.uk/pdbsum/2r2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r2q ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/GBRL1_HUMAN GBRL1_HUMAN]] Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles.<ref>PMID:16431922</ref> <ref>PMID:20404487</ref>
+
[https://www.uniprot.org/uniprot/GBRL1_HUMAN GBRL1_HUMAN] Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles.<ref>PMID:16431922</ref> <ref>PMID:20404487</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 27: Line 27:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bochkarev, A]]
+
[[Category: Bochkarev A]]
-
[[Category: Butler-Cole, C]]
+
[[Category: Butler-Cole C]]
-
[[Category: Davis, T]]
+
[[Category: Davis T]]
-
[[Category: Dhe-Paganon, S]]
+
[[Category: Dhe-Paganon S]]
-
[[Category: Edwards, A M]]
+
[[Category: Edwards AM]]
-
[[Category: Mujib, S]]
+
[[Category: Mujib S]]
-
[[Category: Paramanathan, R]]
+
[[Category: Paramanathan R]]
-
[[Category: Structural genomic]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M]]
+
[[Category: Tempel W]]
-
[[Category: Tempel, W]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J]]
+
-
[[Category: Autophagy]]
+
-
[[Category: Microtubule]]
+
-
[[Category: Protein transport]]
+
-
[[Category: Sgc]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Ubiquitin homolog]]
+

Current revision

Crystal structure of human Gamma-Aminobutyric Acid Receptor-Associated Protein-like 1 (GABARAP1), Isoform CRA_a

PDB ID 2r2q

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools