Journal:Acta Cryst D:S2059798321006628
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<b>Molecular Tour</b><br> | <b>Molecular Tour</b><br> | ||
+ | The thermophilic fungus Malbranchea cinnamomea encodes eight lytic polysaccharide monooxygenases (LPMOs) from the Auxiliary Activities family 9 (AA9), four of which have been shown to oxidatively cleave various polysaccharides. Here we solved the structure of McAA9F, which is a C1/C4-oxidizing LPMO able to cleave both crystalline and soluble glycans. The structure reveals that McAA9F has an overall similar fold as other solved AA9 enzymes, but also has different loop structures than what have previously been linked to activity on soluble oligosaccharides. The structure further contains a rare succinimide substitution that has not been seen in other LPMOs. | ||
<b>References</b><br> | <b>References</b><br> |
Revision as of 14:21, 5 July 2021
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