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2uus

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Current revision (14:55, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2uus' size='340' side='right'caption='[[2uus]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='2uus' size='340' side='right'caption='[[2uus]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2uus]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UUS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2uus]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UUS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YYJ:'>YYJ</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene>, <scene name='pdbligand=PRD_900013:sucrose+octasulfate'>PRD_900013</scene>, <scene name='pdbligand=YYJ:1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose'>YYJ</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2j3p|2j3p]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uus OCA], [https://pdbe.org/2uus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uus RCSB], [https://www.ebi.ac.uk/pdbsum/2uus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uus ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uus OCA], [https://pdbe.org/2uus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uus RCSB], [https://www.ebi.ac.uk/pdbsum/2uus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uus ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FGF1_RAT FGF1_RAT]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
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[https://www.uniprot.org/uniprot/FGF1_RAT FGF1_RAT] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Berezin, V]]
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[[Category: Rattus norvegicus]]
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[[Category: Bock, E]]
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[[Category: Berezin V]]
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[[Category: Gajhede, M]]
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[[Category: Bock E]]
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[[Category: Kiselyov, V]]
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[[Category: Gajhede M]]
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[[Category: Kochoyan, A]]
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[[Category: Kiselyov V]]
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[[Category: Kristensen, O]]
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[[Category: Kochoyan A]]
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[[Category: Kulahin, N]]
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[[Category: Kristensen O]]
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[[Category: Angiogenesis]]
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[[Category: Kulahin N]]
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[[Category: Developmental protein]]
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[[Category: Differentiation]]
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[[Category: Fibroblast growth factor]]
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[[Category: Growth factor]]
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[[Category: Heparin-binding]]
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[[Category: Mitogen]]
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[[Category: Sucrose octasulfate]]
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Current revision

Crystal structure of the rat FGF1-sucrose octasulfate (SOS) complex.

PDB ID 2uus

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