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2vlh

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Current revision (15:24, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2vlh' size='340' side='right'caption='[[2vlh]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2vlh' size='340' side='right'caption='[[2vlh]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VLH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vlh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VLH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PM9:(2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC+ACID'>PM9</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2ez1|2ez1]], [[2tpl|2tpl]], [[2vlf|2vlf]], [[2ez2|2ez2]], [[1tpl|1tpl]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PM9:(2E)-2-{[(Z)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4(1H)-YLIDENE}METHYL]IMINO}-4-(METHYLSULFANYL)BUTANOIC+ACID'>PM9</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Tyrosine_phenol-lyase Tyrosine phenol-lyase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.99.2 4.1.99.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vlh OCA], [https://pdbe.org/2vlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vlh RCSB], [https://www.ebi.ac.uk/pdbsum/2vlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vlh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vlh OCA], [https://pdbe.org/2vlh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vlh RCSB], [https://www.ebi.ac.uk/pdbsum/2vlh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vlh ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPL_CITFR TPL_CITFR]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacterium freundii braak 1928]]
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[[Category: Citrobacter freundii]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Tyrosine phenol-lyase]]
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[[Category: Antson AA]]
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[[Category: Antson, A A]]
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[[Category: Demidkina TV]]
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[[Category: Demidkina, T V]]
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[[Category: Matkovic-Calogovic D]]
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[[Category: Matkovic-Calogovic, D]]
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[[Category: Milic D]]
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[[Category: Milic, D]]
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[[Category: Lyase]]
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[[Category: Plp-dependent enzyme]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Quinonoid intermediate]]
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[[Category: Tyrosine degradation]]
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Current revision

Quinonoid intermediate of Citrobacter freundii tyrosine phenol-lyase formed with methionine

PDB ID 2vlh

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OCA

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