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2vpg

From Proteopedia

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Current revision (15:27, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2vpg' size='340' side='right'caption='[[2vpg]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='2vpg' size='340' side='right'caption='[[2vpg]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vpg]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VPG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vpg]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VPG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DA2:NG,NG-DIMETHYL-L-ARGININE'>DA2</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DA2:NG,NG-DIMETHYL-L-ARGININE'>DA2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vp7|2vp7]], [[2vpb|2vpb]], [[2vpd|2vpd]], [[2vpe|2vpe]]</div></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vpg OCA], [https://pdbe.org/2vpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vpg RCSB], [https://www.ebi.ac.uk/pdbsum/2vpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vpg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vpg OCA], [https://pdbe.org/2vpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vpg RCSB], [https://www.ebi.ac.uk/pdbsum/2vpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vpg ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYGO1_HUMAN PYGO1_HUMAN] Involved in signal transduction through the Wnt pathway.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bienz, M]]
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[[Category: Bienz M]]
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[[Category: Evans, P]]
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[[Category: Evans P]]
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[[Category: Fiedler, M]]
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[[Category: Fiedler M]]
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[[Category: Mieszczanek, J]]
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[[Category: Mieszczanek J]]
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[[Category: Muller, J]]
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[[Category: Muller J]]
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[[Category: Nekrasov, M]]
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[[Category: Nekrasov M]]
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[[Category: Rybin, V]]
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[[Category: Rybin V]]
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[[Category: Sanchez-Barrena, M J]]
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[[Category: Sanchez-Barrena MJ]]
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[[Category: Bcl9 hd1 domain]]
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[[Category: Chromosomal rearrangement]]
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[[Category: Gene regulation]]
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[[Category: Histone h3k4me2]]
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[[Category: Hpygo1 phd domain]]
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[[Category: Metal-binding]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Proto-oncogene]]
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[[Category: Signaling protein]]
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[[Category: Wnt signaling complex]]
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[[Category: Wnt signaling pathway]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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Current revision

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex

PDB ID 2vpg

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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