2wwe

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Current revision (10:18, 20 December 2023) (edit) (undo)
 
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<StructureSection load='2wwe' size='340' side='right'caption='[[2wwe]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
<StructureSection load='2wwe' size='340' side='right'caption='[[2wwe]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWE FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwe OCA], [https://pdbe.org/2wwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwe RCSB], [https://www.ebi.ac.uk/pdbsum/2wwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwe ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwe OCA], [https://pdbe.org/2wwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwe RCSB], [https://www.ebi.ac.uk/pdbsum/2wwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwe ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/P3C2G_HUMAN P3C2G_HUMAN] Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers (By similarity). May play a role in SDF1A-stimulated chemotaxis (By similarity).[UniProtKB:O70167][UniProtKB:O70173]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Berg, S Van Der]]
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[[Category: Berglund H]]
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[[Category: Berglund, H]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Collins R]]
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[[Category: Collins, R]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M]]
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[[Category: Flodin S]]
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[[Category: Flodin, S]]
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[[Category: Flores A]]
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[[Category: Flores, A]]
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[[Category: Graslund S]]
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[[Category: Graslund, S]]
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[[Category: Hammarstrom M]]
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[[Category: Hammarstrom, M]]
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[[Category: Johansson A]]
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[[Category: Johansson, A]]
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[[Category: Johansson I]]
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[[Category: Johansson, I]]
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[[Category: Kallas A]]
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[[Category: Kallas, A]]
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[[Category: Karlberg T]]
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[[Category: Karlberg, T]]
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[[Category: Kotyenova T]]
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[[Category: Kotyenova, T]]
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[[Category: Kotzch A]]
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[[Category: Kotzch, A]]
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[[Category: Kraulis P]]
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[[Category: Kraulis, P]]
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[[Category: Markova N]]
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[[Category: Markova, N]]
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[[Category: Moche M]]
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[[Category: Moche, M]]
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[[Category: Nielsen TK]]
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[[Category: Nielsen, T K]]
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[[Category: Nordlund P]]
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[[Category: Nordlund, P]]
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[[Category: Nyman T]]
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[[Category: Nyman, T]]
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[[Category: Persson C]]
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[[Category: Persson, C]]
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[[Category: Roos AK]]
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[[Category: Roos, A K]]
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[[Category: Schuler H]]
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[[Category: Structural genomic]]
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[[Category: Schutz P]]
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[[Category: Schuler, H]]
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[[Category: Siponen MI]]
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[[Category: Schutz, P]]
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[[Category: Svensson L]]
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[[Category: Siponen, M I]]
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[[Category: Thorsell AG]]
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[[Category: Svensson, L]]
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[[Category: Tresaugues L]]
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[[Category: Thorsell, A G]]
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[[Category: Van Der Berg S]]
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[[Category: Tresaugues, L]]
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[[Category: Wahlberg E]]
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[[Category: Wahlberg, E]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Welin M]]
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[[Category: Welin, M]]
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[[Category: Wisniewska M]]
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[[Category: Wisniewska, M]]
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[[Category: Atp-binding]]
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[[Category: Class 2 pi3k]]
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[[Category: Kinase]]
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[[Category: Membrane]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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[[Category: Pik3c2g]]
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[[Category: Polymorphism]]
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[[Category: Px-domain]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the phox homology domain of human phosphoinositide-3-kinase-C2-gamma

PDB ID 2wwe

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