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6vta

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Current revision (08:19, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6vta' size='340' side='right'caption='[[6vta]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
<StructureSection load='6vta' size='340' side='right'caption='[[6vta]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6vta]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"proteus_stuartii"_buttiaux_et_al._1954 "proteus stuartii" buttiaux et al. 1954]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VTA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6vta]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Providencia_stuartii Providencia stuartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VTA FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=AKN:(2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S+,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide'>AKN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.42&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[6vou|6vou]], [[6vr2|6vr2]], [[6vr3|6vr3]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=AKN:(2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S+,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide'>AKN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aac ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=588 "Proteus stuartii" Buttiaux et al. 1954])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Gentamicin_2'-N-acetyltransferase Gentamicin 2'-N-acetyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.59 2.3.1.59] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vta OCA], [https://pdbe.org/6vta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vta RCSB], [https://www.ebi.ac.uk/pdbsum/6vta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vta ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vta OCA], [https://pdbe.org/6vta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vta RCSB], [https://www.ebi.ac.uk/pdbsum/6vta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vta ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AAC2_PROST AAC2_PROST]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Proteus stuartii buttiaux et al. 1954]]
 
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[[Category: Gentamicin 2'-N-acetyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bassenden, A V]]
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[[Category: Providencia stuartii]]
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[[Category: Berghuis, A M]]
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[[Category: Bassenden AV]]
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[[Category: Acetyltransferase]]
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[[Category: Berghuis AM]]
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[[Category: Gnat superfamily]]
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[[Category: Transferase]]
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Current revision

Aminoglycoside N-2'-Acetyltransferase-Ia [AAC(2')-Ia] in complex with amikacin and acetyl-CoA

PDB ID 6vta

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