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Ets1

From Proteopedia

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Current revision (11:29, 23 February 2023) (edit) (undo)
 
Line 31: Line 31:
**[[6da1]], [[6dat]] – mETS1 + SSR peptide <br />
**[[6da1]], [[6dat]] – mETS1 + SSR peptide <br />
-
*Ets1 ternary complexes
+
*Ets1 higher complexes
**[[1k78]] – hETS1 ETS domain + paired box protein Pax5 + MB-1 promoter DNA - NMR<br />
**[[1k78]] – hETS1 ETS domain + paired box protein Pax5 + MB-1 promoter DNA - NMR<br />
Line 37: Line 37:
**[[4lg0]] – hETS1 residues 280-441 + cadherin promoter DNA + forkhead box protein<br />
**[[4lg0]] – hETS1 residues 280-441 + cadherin promoter DNA + forkhead box protein<br />
**[[1mdm]] – mETS1 ETS domain + paired box protein Pax5 + MB-1 promoter DNA <br />
**[[1mdm]] – mETS1 ETS domain + paired box protein Pax5 + MB-1 promoter DNA <br />
 +
**[[3wu1]] – hETS1 276-441 (mutant) + RUNX1 + DNA <br />
 +
**[[3wts]], [[3wtt]], [[3wtu]], [[3wtv]], [[3wtw]], [[3wtx]], [[3wty]] – hETS1 276-441 (mutant) + RUNX1 + CBF beta + DNA <br />
}}
}}

Current revision

Structure of mouse Ets1 ETS domain (green) complex with paired box protein Pax5 (magenta) and MB-1 promoter DNA (PDB code 1mdm).

Drag the structure with the mouse to rotate

3D Structures of Ets1

Updated on 23-February-2023

References

  1. Dwyer J, Li H, Xu D, Liu JP. Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family. Ann N Y Acad Sci. 2007 Oct;1114:36-47. PMID:17986575 doi:http://dx.doi.org/10.1196/annals.1396.022
  2. Garvie CW, Pufall MA, Graves BJ, Wolberger C. Structural analysis of the autoinhibition of Ets-1 and its role in protein partnerships. J Biol Chem. 2002 Nov 22;277(47):45529-36. Epub 2002 Sep 6. PMID:12221090 doi:10.1074/jbc.M206327200

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Michal Harel, Alexander Berchansky, Jaime Prilusky

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