1ds9

<StructureSection load='1ds9' size='340' side='right'caption='[[1ds9]], [[NMR_Ensembles_of_Models | 17 NMR models]]' scene=''>

<table><tr><td colspan='2'>[[1ds9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlre Chlre]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DS9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DS9 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ds9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ds9 OCA], [https://pdbe.org/1ds9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ds9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ds9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ds9 ProSAT]</span></td></tr>

[[https://www.uniprot.org/uniprot/DNAL1_CHLRE DNAL1_CHLRE]] Associates with the gamma heavy chain in the outer arm dynein. May target p45 polypeptide (an 45 kDa axonemal component) to the motor domain of the gamma heavy chain dynein.<ref>PMID:10353837</ref>

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== Publication Abstract from PubMed ==

Dyneins are molecular motors that translocate towards the minus ends of microtubules. In Chlamydomonas flagellar outer arm dynein, light chain 1 (LC1) associates with the nucleotide binding region within the gamma heavy chain motor domain and consists of a central leucine-rich repeat section that folds as a cylindrical right handed spiral formed from six beta-beta-alpha motifs. This central cylinder is flanked by terminal helical subdomains. The C-terminal helical domain juts out from the cylinder and is adjacent to a hydrophobic surface within the repeat region that is proposed to interact with the dynein heavy chain. The position of the C-terminal domain on LC1 and the unexpected structural similarity between LC1 and U2A' from the human spliceosome suggest that this domain interacts with the dynein motor domain.

Solution structure of a dynein motor domain associated light chain.,Wu H, Maciejewski MW, Marintchev A, Benashski SE, Mullen GP, King SM Nat Struct Biol. 2000 Jul;7(7):575-9. PMID:10876244<ref>PMID:10876244</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 1ds9" style="background-color:#fffaf0;"></div>

[[Category: Chlre]]

[[Category: Benashski, S E]]

[[Category: King, S M]]

[[Category: Maciejewski, M W]]

[[Category: Marintchev, A]]

[[Category: Mullen, G P]]

[[Category: Wu, H W]]

[[Category: Leucine-rich repeat]]