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6xbo

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Current revision (14:49, 18 October 2023) (edit) (undo)
 
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<StructureSection load='6xbo' size='340' side='right'caption='[[6xbo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='6xbo' size='340' side='right'caption='[[6xbo]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6xbo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XBO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6xbo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XBO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XBO FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Slc35a1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2PE:NONAETHYLENE+GLYCOL'>2PE</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xbo OCA], [https://pdbe.org/6xbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xbo RCSB], [https://www.ebi.ac.uk/pdbsum/6xbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xbo ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xbo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xbo OCA], [https://pdbe.org/6xbo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xbo RCSB], [https://www.ebi.ac.uk/pdbsum/6xbo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xbo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/S35A1_MOUSE S35A1_MOUSE]] Transport CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function.
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[https://www.uniprot.org/uniprot/S35A1_MOUSE S35A1_MOUSE] Transport CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Ahuja, S]]
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[[Category: Ahuja S]]
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[[Category: Whorton, M R]]
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[[Category: Whorton MR]]
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[[Category: 5-methyl cmp]]
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[[Category: Glycobiology]]
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[[Category: Sialic acid]]
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[[Category: Transport protein]]
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[[Category: Transporter]]
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Current revision

X-ray crystal structure of the mouse CMP-Sialic acid transporter in complex with 5-methyl CMP

PDB ID 6xbo

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