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1h05

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Current revision (12:11, 13 December 2023) (edit) (undo)
 
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<StructureSection load='1h05' size='340' side='right'caption='[[1h05]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='1h05' size='340' side='right'caption='[[1h05]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1h05]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H05 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1h05]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H05 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2dhq|2dhq]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h05 OCA], [https://pdbe.org/1h05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h05 RCSB], [https://www.ebi.ac.uk/pdbsum/1h05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h05 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h05 OCA], [https://pdbe.org/1h05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h05 RCSB], [https://www.ebi.ac.uk/pdbsum/1h05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h05 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU]] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
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[https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-dehydroquinate dehydratase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Myctu]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Coggins, J R]]
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[[Category: Coggins JR]]
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[[Category: Lapthorn, A J]]
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[[Category: Lapthorn AJ]]
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[[Category: Roszak, A W]]
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[[Category: Roszak AW]]
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[[Category: Alpha/beta protein]]
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[[Category: Aromatic amino acid biosynthesis]]
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[[Category: Dehydratase]]
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[[Category: Lyase]]
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[[Category: Shikimate pathway]]
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Current revision

3-DEHYDROQUINATE DEHYDRATASE FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH SULPHATE

PDB ID 1h05

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