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Bone morphogenetic protein

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== Function ==
== Function ==
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'''Bone morphogenetic protein''' (BMP) are growth factors which can induce formation of bone and cartllage'<ref>PMID:19900831</ref>. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. See also [[Growth factors]] and [[Growth differentiation factor]].
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'''Bone morphogenetic protein''' (BMP) are growth factors which can induce formation of bone and cartllage'<ref>PMID:19900831</ref>. Over 20 BMPs are known at present. BMP is part of the Transforming Growth Factor-β (TGF-β) family of proteins. For details on BMP-7 see [[Student Projects for UMass Chemistry 423 Spring 2012-4]]. See also [[Growth factors]], [[Enzyme-linked receptor]] and [[Growth differentiation factor]].
== Relevance ==
== Relevance ==

Revision as of 10:39, 9 January 2023

Human BMP-2 (grey and green) complex with BMP receptor extracellular domain (yellow and pink) (PDB entry 2qja)

Drag the structure with the mouse to rotate

References

  1. Reddi AH, Reddi A. Bone morphogenetic proteins (BMPs): from morphogens to metabologens. Cytokine Growth Factor Rev. 2009 Oct-Dec;20(5-6):341-2. doi:, 10.1016/j.cytogfr.2009.10.015. Epub 2009 Nov 8. PMID:19900831 doi:http://dx.doi.org/10.1016/j.cytogfr.2009.10.015
  2. Mitu G, Hirschberg R. Bone morphogenetic protein-7 (BMP7) in chronic kidney disease. Front Biosci. 2008 May 1;13:4726-39. PMID:18508541

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