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1ijl

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Current revision (07:10, 25 October 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ijl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IJL FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ijl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinagkistrodon_acutus Deinagkistrodon acutus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IJL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IJL FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1psj|1psj]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ijl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ijl OCA], [https://pdbe.org/1ijl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ijl RCSB], [https://www.ebi.ac.uk/pdbsum/1ijl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ijl ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ijl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ijl OCA], [https://pdbe.org/1ijl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ijl RCSB], [https://www.ebi.ac.uk/pdbsum/1ijl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ijl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PA2A_DEIAC PA2A_DEIAC]] Snake venom phospholipase A2 (PLA2) that inhibits ADP-induced platelet aggregation. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<ref>PMID:8931260</ref>
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[https://www.uniprot.org/uniprot/PA2A_DEIAC PA2A_DEIAC] Snake venom phospholipase A2 (PLA2) that inhibits ADP-induced platelet aggregation. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<ref>PMID:8931260</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Deinagkistrodon acutus]]
[[Category: Deinagkistrodon acutus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gu, L]]
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[[Category: Gu L]]
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[[Category: Lin, Z]]
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[[Category: Lin Z]]
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[[Category: Song, S]]
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[[Category: Song S]]
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[[Category: Zhang, H]]
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[[Category: Zhang H]]
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[[Category: Zhou, Y]]
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[[Category: Zhou Y]]
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[[Category: Calcium binding loop]]
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[[Category: Hydrolase]]
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[[Category: One two strand beta sheet]]
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[[Category: Three long helix]]
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Current revision

Crystal structure of acidic phospholipase A2 from deinagkistrodon acutus

PDB ID 1ijl

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