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5w3w

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Current revision (14:06, 4 October 2023) (edit) (undo)
 
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<StructureSection load='5w3w' size='340' side='right'caption='[[5w3w]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
<StructureSection load='5w3w' size='340' side='right'caption='[[5w3w]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5w3w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W3W FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5w3w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5W3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5W3W FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5vri|5vri]], [[5vrk|5vrk]], [[5vsa|5vsa]], [[5w3u|5w3u]], [[5w3z|5w3z]]</div></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aryldialkylphosphatase Aryldialkylphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.8.1 3.1.8.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w3w OCA], [https://pdbe.org/5w3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w3w RCSB], [https://www.ebi.ac.uk/pdbsum/5w3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w3w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5w3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5w3w OCA], [https://pdbe.org/5w3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5w3w RCSB], [https://www.ebi.ac.uk/pdbsum/5w3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5w3w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/PHP_SULSO PHP_SULSO]] Has a low paraoxonase activity. Also active, but with a lower activity, against other oregano-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion.<ref>PMID:15909078</ref>
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[https://www.uniprot.org/uniprot/PHP_SACS2 PHP_SACS2] Has a low paraoxonase activity. Also active, but with a lower activity, against other organo-phosphorus insecticides such as Dursban, Coumaphos, pNP-butanoate or parathion.<ref>PMID:15909078</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aryldialkylphosphatase]]
 
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[[Category: Atcc 35091]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bergonzi, C]]
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[[Category: Saccharolobus solfataricus]]
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[[Category: Chabriere, E]]
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[[Category: Bergonzi C]]
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[[Category: Daude, D]]
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[[Category: Chabriere E]]
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[[Category: Elias, M]]
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[[Category: Daude D]]
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[[Category: Gotthard, G]]
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[[Category: Elias M]]
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[[Category: Hiblot, J]]
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[[Category: Gotthard G]]
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[[Category: Jacquet, P]]
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[[Category: Hiblot J]]
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[[Category: Hydrolase]]
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[[Category: Jacquet P]]
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[[Category: Insecticides]]
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[[Category: Lactonase]]
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[[Category: Mutant]]
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[[Category: Organophosphate]]
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[[Category: Organophosphorous]]
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[[Category: Phosphotriesterase]]
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[[Category: Quorum sensing]]
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Current revision

Crystal structure of SsoPox AsD6 mutant (V27A-Y97W-L228M-W263M) - open form

PDB ID 5w3w

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