7a2f
From Proteopedia
(Difference between revisions)
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==Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656== | ==Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656== | ||
| - | <StructureSection load='7a2f' size='340' side='right'caption='[[7a2f]]' scene=''> | + | <StructureSection load='7a2f' size='340' side='right'caption='[[7a2f]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A2F FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7a2f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A2F FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a2f OCA], [https://pdbe.org/7a2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a2f RCSB], [https://www.ebi.ac.uk/pdbsum/7a2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a2f ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GAI:GUANIDINE'>GAI</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=QWZ:1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl)ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one'>QWZ</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a2f OCA], [https://pdbe.org/7a2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a2f RCSB], [https://www.ebi.ac.uk/pdbsum/7a2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a2f ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q8WQX9_9TRYP Q8WQX9_9TRYP] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Trypanosoma brucei]] | ||
[[Category: Blaazer AR]] | [[Category: Blaazer AR]] | ||
[[Category: Brown DG]] | [[Category: Brown DG]] | ||
Current revision
Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656
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