1f62

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{{STRUCTURE_1f62| PDB=1f62 | SCENE= }}
{{STRUCTURE_1f62| PDB=1f62 | SCENE= }}
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'''WSTF-PHD'''
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===WSTF-PHD===
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==Overview==
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The PHD (plant homeo domain) is a approximately 50-residue motif found mainly in proteins involved in eukaryotic transcription regulation. The characteristic sequence feature is a conserved Cys(4)-HisCys(3) zinc binding motif. We have determined the solution structure of the PHD motif from the human Williams-Beuren syndrome transcription factor (WSTF) protein. The domain folds into an interleaved zinc finger which binds two Zn(2+) in a similar manner to that of the RING and FYVE domains. The structure reveals a conserved zinc-binding core, together with two variable loops that are likely candidates for interactions between the various PHD domains and their specific ligands.
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(as it appears on PubMed at http://www.pubmed.gov), where 11124022 is the PubMed ID number.
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{{ABSTRACT_PUBMED_11124022}}
==About this Structure==
==About this Structure==
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1F62 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F62 OCA].
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1F62 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F62 OCA].
==Reference==
==Reference==
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[[Category: Wright, P E.]]
[[Category: Wright, P E.]]
[[Category: Zn-finger]]
[[Category: Zn-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:56:55 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 02:45:42 2008''

Revision as of 23:45, 30 June 2008

Image:1f62.png

Template:STRUCTURE 1f62

WSTF-PHD

Template:ABSTRACT PUBMED 11124022

About this Structure

1F62 is a Single protein structure of sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

Structure of the PHD zinc finger from human Williams-Beuren syndrome transcription factor., Pascual J, Martinez-Yamout M, Dyson HJ, Wright PE, J Mol Biol. 2000 Dec 15;304(5):723-9. PMID:11124022

Page seeded by OCA on Tue Jul 1 02:45:42 2008

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